BDBM350904 3-Phenyl-2-(4-pyridylmethylthio)-4-oxo-3,4-dihydroquinazoline::US9796687, Compound 27

SMILES O=c1n(c(SCc2ccncc2)nc2ccccc12)-c1ccccc1

InChI Key InChIKey=WVIORRIIXYVEIF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350904   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
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US Patent
LigandPNGBDBM350904(3-Phenyl-2-(4-pyridylmethylthio)-4-oxo-3,4-dihydro...)
Affinity DataIC50:  2.60E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In DepthDetails US Patent