BDBM351930 Preparation of 5-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-2-((2-methoxyethyl)methylamino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenylmethanol ::US9796732, Compound 6

SMILES COCCN(C)c1nc(N2C3CCC2COC3)c2ccc(nc2n1)-c1ccc(OC)c(CO)c1

InChI Key InChIKey=QCBSQURWTMLVJE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351930   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Shandong Luoxin Pharmaceutical Group Stock

US Patent
LigandPNGBDBM351930(Preparation of 5-(4-(3-oxa-8-azabicyclo[3.2.1]octa...)
Affinity DataIC50:  22nMAssay Description:The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent