BDBM352758 (S)-1,1,1-trifluoro-2-methylpropan-2-yl (2-(2-acetamido-2-methylpropyl)-4- ((3,4-difluorophenyl)sulfonyl)-3,4- dihydro-2H-benzo[b][1,4]oxazin-6- yl)carbamate::US10745364, Example 57E::US9809561, 57E
SMILES CC(=O)NC(C)(C)C[C@H]1CN(c2cc(NC(=O)OC(C)(C)C(F)(F)F)ccc2O1)S(=O)(=O)c1ccc(F)c(F)c1
InChI Key InChIKey=PWDWALSZMPZRHO-INIZCTEOSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 352758
Affinity DataIC50: 4.17nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair