BDBM354316 1-(3-(tert-Butyl)-1-(3-((1-oxidophospholan-1-yl)methyl)phenyl)-1H-pyrazol-5-yl)-3-(4-((2-(phenylamino)pyridin-4-yl)oxy)naphthalen-1-yl)urea::US9796742, Example 44

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccccc4)c3)c3ccccc23)n(n1)-c1cccc(CP2(=O)CCCC2)c1

InChI Key InChIKey=QHGNHRHTSCGQIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354316   

TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM354316(1-(3-(tert-Butyl)-1-(3-((1-oxidophospholan-1-yl)me...)
Affinity DataIC50:  8.04E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3?? enzyme isoform (Invitrogen), are evaluated by determining the level of ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM354316(1-(3-(tert-Butyl)-1-(3-((1-oxidophospholan-1-yl)me...)
Affinity DataIC50:  201nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent