BDBM354591 Phenyl 7-[(3S)-3-[(dimethylamino)methyl]-1,2,3,4-tetrahydroisoquinoline-2-carbonyl]-6-{4-[(4-hydroxyphenyl)(methyl)carbamoyl]-1,5-dimethyl-1H-pyrrol-2-yl}-1,2,3,4-tetrahydroisoquinoline-2-carboxylate::US9809574, Example 211

SMILES CN(C)C[C@@H]1Cc2ccccc2CN1C(=O)c1cc2CN(CCc2cc1-c1cc(C(=O)N(C)c2ccc(O)cc2)c(C)n1C)C(=O)Oc1ccccc1

InChI Key InChIKey=WVHNAQGYWMIUAH-UMSFTDKQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354591   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
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US Patent
LigandPNGBDBM354591(Phenyl 7-[(3S)-3-[(dimethylamino)methyl]-1,2,3,4-t...)
Affinity DataIC50:  3.40nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent