BDBM354913 2-Methyl-2-(1H-pyrazol-1-yl)propanimidamide acetate::US9815796, Example 4
SMILES COc1ccc(Cc2nc(cc(=O)[nH]2)C(=O)N[C@H](C)c2ccc(cc2)C(F)(F)F)cc1OC
InChI Key
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 354913
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.520nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Affinity DataKi: 0.560nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair