BDBM355348 2-cyclopropyl-N-[(1R)-2,2-dimethyl- 1-{4- [(trifluoromethyl)sulfanyl]phenyl}pro- pyl]-6-oxo-1,6-dihydropyrimidine-4- carboxamide::US9815796, Example 439
SMILES CC(C)(C)[C@@H](NC(=O)c1cc(=O)[nH]c(n1)C1CC1)c1ccc(SC(F)(F)F)cc1
InChI Key
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 355348
Affinity DataKi: 1nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 2nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair