BDBM355366 N-{(1R)-2,2-dimethyl-1-[4- (trifluoromethyl)phenyl]propyl}-2- (3-fluoro-4-methoxybenzyl)-6-oxo- 1,6-dihydropyrimidine-4- carboxamide::US9815796, Example 457
SMILES COc1ccc(Cc2nc(cc(=O)[nH]2)C(=O)N[C@@H](c2ccc(cc2)C(F)(F)F)C(C)(C)C)cc1F
InChI Key
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 355366
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.640nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair