BDBM355445 N-[(1R)-1-(4-cyclopropylphenyl)- 2,2-dimethylpropyl]-6-oxo-2- phenyl-1,6-dihydropyrimidine-4- carboxamide::US9815796, Example 536

SMILES CC(C)(C)[C@@H](NC(=O)c1cc(=O)[nH]c(n1)-c1ccccc1)c1ccc(cc1)C1CC1

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355445   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM355445(N-[(1R)-1-(4-cyclopropylphenyl)- 2,2-dimethylpropy...)
Affinity DataKi:  0.510nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent