BDBM355552 N-{(1S)-1-[2-chloro-4- (trifluoromethyl)phenyl]-2-hydroxy- 1-methylethyl}-6-oxo-2-phenyl-1,6- dihydropyrimidine-4-carboxamide::US9815796, Example 643
SMILES C[C@](CO)(NC(=O)c1cc(=O)[nH]c(n1)-c1ccccc1)c1ccc(cc1Cl)C(F)(F)F
InChI Key
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 355552
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.5nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair