BDBM355791 N-Cyclopropyl-3-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridine-2-carboxamide::US9815832, 68

SMILES Fc1ccc(cc1)-n1c(nc2cccnc12)C(=O)NC1CC1

InChI Key InChIKey=VXOZXGHOYRHTAZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355791   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM355791(N-Cyclopropyl-3-(4-fluorophenyl)-3H-imidazo[4,5-b]...)
Affinity DataIC50:  1.19E+4nMAssay Description:The PDE4B and 4D assays use scintillation proximity assay (SPA) technology to measure the inhibition of human recombinant PDE4B and PDE4D enzyme acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM355791(N-Cyclopropyl-3-(4-fluorophenyl)-3H-imidazo[4,5-b]...)
Affinity DataIC50:  219nMAssay Description:The PDE4B and 4D assays use scintillation proximity assay (SPA) technology to measure the inhibition of human recombinant PDE4B and PDE4D enzyme acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent