BDBM355840 US9815836, Compound 25

SMILES Cn1cc2NC(=O)c3cccc(n3)-c3cnn(C\C=C\CCCNC(=O)c2n1)c3

InChI Key InChIKey=LUZCLIOCMADQAB-HWKANZROSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355840   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM355840(US9815836, Compound 25)
Affinity DataIC50: <100nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK4 (1-460)).In this assay, IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 1 [194-712](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM355840(US9815836, Compound 25)
Affinity DataIC50: <100nMAssay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712))In this assay, IRAK1 hydrolyses ATP and autophosphorylates. Measurement of IRAK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent