BDBM355870 N-(4-((5-(3-amino-4-methyl)-5-fluorophenyl)pyrrolo[1,2-b]pyridazin-4-yl)oxy)-3-fluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide::US9815840, Example 78

SMILES Cc1ccc(cc1N)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12

InChI Key InChIKey=XTGYAQRBVMMSDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355870   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
The Asan Foundation

US Patent
LigandPNGBDBM355870(N-(4-((5-(3-amino-4-methyl)-5-fluorophenyl)pyrrolo...)
Affinity DataIC50: <40nMAssay Description:The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent