BDBM355901 1-(5-chloro-6- ethoxypyridin-3-yl)- 3-(2-chloro-7- isopropylpyrazolo[1, 5-a]pyrimidin-6- yl)urea::US10442808, Example 25::US9815842, Example 25
SMILES CCOc1ncc(NC(=O)Nc2cnc3cc(Cl)nn3c2C(C)C)cc1Cl
InChI Key InChIKey=RJZDNSHULBVKFY-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 355901
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1 [329-824](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 0.00500nMAssay Description:The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 0.00500nMAssay Description:IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...More data for this Ligand-Target Pair