BDBM35850 acrylic acid derivative, 8

SMILES COc1ccc(\C=C\C(O)=O)c(OCCC2(C)CCc3c(C)c(O)c(C)c(C)c3O2)c1

InChI Key InChIKey=YQMZJMKFBPBGJZ-VQHVLOKHSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 35850   

TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Ono Pharmaceutical

LigandPNGBDBM35850(acrylic acid derivative, 8)
Affinity DataKi:  920nMAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Ono Pharmaceutical

LigandPNGBDBM35850(acrylic acid derivative, 8)
Affinity DataKi:  6.80E+3nM ΔG°:  -7.04kcal/molepH: 6.0 T: 2°CAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Mus musculus (Mouse))
Ono Pharmaceutical

LigandPNGBDBM35850(acrylic acid derivative, 8)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 6.0 T: 2°CAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Ono Pharmaceutical

LigandPNGBDBM35850(acrylic acid derivative, 8)
Affinity DataKi: >1.00E+4nM EC50: >1.00E+4nMAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed