BDBM35853 acrylic acid derivative, 11

SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1OCCc1cc2ccccc2o1

InChI Key InChIKey=WWCNZHFOUQGWKB-BQYQJAHWSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 35853   

TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Ono Pharmaceutical

LigandPNGBDBM35853(acrylic acid derivative, 11)
Affinity DataKi:  44nM EC50:  330nMAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Ono Pharmaceutical

LigandPNGBDBM35853(acrylic acid derivative, 11)
Affinity DataKi:  4.30E+3nMAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Mus musculus (Mouse))
Ono Pharmaceutical

LigandPNGBDBM35853(acrylic acid derivative, 11)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 6.0 T: 2°CAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Ono Pharmaceutical

LigandPNGBDBM35853(acrylic acid derivative, 11)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 6.0 T: 2°CAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed