BDBM358674 N-(3-(4-(5-(4-amino-5- (trifluoromethyl)pyrrolo[2,1-f][1,2,4] triazin-7-yl)-2-fluorophenyl)-2,2- dimethyl-3-oxopiperazin-1-yl)-3- oxopropyl)methanesulfonamide::US10214537, Example 751

SMILES CC1(C)N(CCN(C1=O)c1cc(ccc1F)-c1cc(c2c(N)ncnn12)C(F)(F)F)C(=O)CCNS(C)(=O)=O

InChI Key InChIKey=XTEFHKMLMVEGMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 358674   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM358674(N-(3-(4-(5-(4-amino-5- (trifluoromethyl)pyrrolo[2,...)
Affinity DataIC50:  0.5nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent