BDBM360451 (1S,2S)-2-(4-methoxyphenyl)-N-((5- (3-methoxyphenyl)isoquinolin-8- yl)methyl)cyclopropanecarboxamide::US9828369, Example 106::US9828369, Example 23

SMILES COc1ccc(cc1)C1CC1C(=O)NCc1ccc(-c2cccc(OC)c2)c2ccncc12

InChI Key InChIKey=JYIFLWOQDGVZHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 360451   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharpe & Dohme

US Patent
LigandPNGBDBM360451((1S,2S)-2-(4-methoxyphenyl)-N-((5- (3-methoxypheny...)
Affinity DataIC50:  537nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharpe & Dohme

US Patent
LigandPNGBDBM360451((1S,2S)-2-(4-methoxyphenyl)-N-((5- (3-methoxypheny...)
Affinity DataIC50:  9.96E+3nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent