BDBM361912 N-[(1S)-1-{[(cis)-2,6- dimethylmorpholin-4- yl]carbonyl}propyl]-9-ethyl-8-(2- methylpyrimidin-5-yl)-9H-purin- 6-amine::US10221178, Compound 2-6
SMILES CC[C@H](Nc1ncnc2n(CC)c(nc12)-c1cnc(C)nc1)C(=O)N1C[C@H](C)O[C@H](C)C1
InChI Key InChIKey=BCFBXBYJWKHDKA-VBQJREDUSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 361912
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 6.10nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair