BDBM362179 US10272077, Example 9 from U.S. Pat. No. 7,390,798::US9833448, Example 9 from U.S. Pat. No. 7,390,798
SMILES Fc1cccc([C@@H]2CC[C@@H](NC(=O)c3ccc4CC5(Cc4c3)C(=O)Nc3ncccc53)C(=O)N(CC(F)(F)F)C2)c1F
InChI Key InChIKey=SLMBMWIBJWYEMS-HZWJCNPPSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 362179
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 1.90nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 1.90nMAssay Description:Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-methylxanthine. Cells were then plated in a 384-wel...More data for this Ligand-Target Pair