BDBM3626 5-[(3-Bromophenyl)amino]-1-[2-(N,N-dimethylamino)ethyl]pyrazolo[4,3-g]quinazoline::N-(3-bromophenyl)-1-[2-(dimethylamino)ethyl]-1H-pyrazolo[4,3-g]quinazolin-5-amine::Pyrazoloquinazoline deriv. 2d

SMILES CN(C)CCn1ncc2cc3c(Nc4cccc(Br)c4)ncnc3cc12

InChI Key InChIKey=LBVQCWSCVVKPQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3626   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM3626(5-[(3-Bromophenyl)amino]-1-[2-(N,N-dimethylamino)e...)
Affinity DataIC50:  263nMAssay Description:Inhibition autophosphorylation of EGFR in human DiFi cells after 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM3626(5-[(3-Bromophenyl)amino]-1-[2-(N,N-dimethylamino)e...)
Affinity DataIC50:  40nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed