BDBM362646 US10562916, Compound 208::US9834564, Compound 208

SMILES Cc1nc(CCc2nc3c(ccc4ncccc34)n2C)nc(C)c1Cl

InChI Key InChIKey=IHPZZJNLWGSAOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362646   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharmaceuticals

US Patent
LigandPNGBDBM362646(US10562916, Compound 208 | US9834564, Compound 208)
Affinity DataIC50: <500nMAssay Description:In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharmaceuticals

US Patent
LigandPNGBDBM362646(US10562916, Compound 208 | US9834564, Compound 208)
Affinity DataIC50: <500nMAssay Description:The activities of the compounds were determined using the Molecular Devices IMAP PDE Fluorescence Polarization assay using recombinant human PDE-10 e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent