BDBM364546 (4bR,6S,8aS,9R)-11-(cyclopropylmethyl)- 3,6-dihydroxy-5,6,7,8,9,10-hexahydro-9,4b- (epiminoethano)-8a,6- (epoxymethano)phenanthren-15-one::US9862726, Compound 9

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(CC5(O)CC[C@@]34OC5=O)c2c1

InChI Key InChIKey=VHGDSYISPRNXMO-QKNTZHCYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 364546   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM364546((4bR,6S,8aS,9R)-11-(cyclopropylmethyl)- 3,6-dihydr...)
Affinity DataKi:  0.950nMAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM364546((4bR,6S,8aS,9R)-11-(cyclopropylmethyl)- 3,6-dihydr...)
Affinity DataKi:  10.1nMAssay Description:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg mem...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent