BDBM365362 US10633373, Example 67::US10669265, Example 67::US9868726, Example 67::dimethyl [6-amino-5-(4-{[(2- fluoro-5- methylphenyl)carbamoyl]amino} phenyl)pyridin-3- yl]phosphonate

SMILES COP(=O)(OC)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1

InChI Key InChIKey=LAVZLEWUCBFRHA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 365362   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365362(US10633373, Example 67 | US10669265, Example 67 | ...)
Affinity DataIC50:  133nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365362(US10633373, Example 67 | US10669265, Example 67 | ...)
Affinity DataIC50:  133nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365362(US10633373, Example 67 | US10669265, Example 67 | ...)
Affinity DataIC50:  133nMAssay Description:VEGFR2: Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent