BDBM371829 2-(8-(1H-Indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)-N-phenylacetamide::US10239876, Example 16::US10239876, Example 6::US10435407, Example 6

SMILES O=C(CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O)Nc1ccccc1

InChI Key InChIKey=DTDFVCJCQKMAKM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 371829   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM371829(2-(8-(1H-Indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8...)
Affinity DataIC50:  10.6nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM371829(2-(8-(1H-Indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8...)
Affinity DataIC50:  10.6nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM371829(2-(8-(1H-Indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8...)
Affinity DataIC50:  496nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent