BDBM372273 6-(3,4-dimethylpyrimido [4',5':4,5]thieno[2,3-c] pyridazin-8-yl)-2-oxa-6- azaspiro[3.3]heptane::US10239887, Cpd. No. 13

SMILES Cc1nnc2sc3c(ncnc3c2c1C)N1CC2(COC2)C1

InChI Key InChIKey=NGVQCUKQHWFSFL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372273   

TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt University

US Patent
LigandPNGBDBM372273(6-(3,4-dimethylpyrimido [4',5':4,5]thieno[2,3-c] p...)
Affinity DataEC50:  231nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM372273(6-(3,4-dimethylpyrimido [4',5':4,5]thieno[2,3-c] p...)
Affinity DataEC50:  123nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent