BDBM373106 1-(2- phenylimidazo[1,2- a]pyridin-3-yl)-3-[4- (trifluoromethyl) phenyl]urea::US9896447, Compound 23

SMILES FC(F)(F)c1ccc(NC(=O)Nc2c(nc3ccccn23)-c2ccccc2)cc1

InChI Key InChIKey=FVYJLKKQTXNBOW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373106   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373106(1-(2- phenylimidazo[1,2- a]pyridin-3-yl)-3-[4- (tr...)
Affinity DataIC50:  4.30E+3nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent