BDBM373107 1-(2- phenylimidazo[1,2- a]pyridin-3-yl)-3-(2- phenylpyridin-3- yl)urea::US9896447, Compound 24

SMILES O=C(Nc1c(nc2ccccn12)-c1ccccc1)Nc1cccnc1-c1ccccc1

InChI Key InChIKey=BAQKMIUQGKTCSV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373107   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373107(1-(2- phenylimidazo[1,2- a]pyridin-3-yl)-3-(2- phe...)
Affinity DataIC50:  450nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent