BDBM373799 (R)-4-((1-benzylpyrrolidin-3-yl)amino)-3-chloro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide 2,2,2-trifluoroacetate::US10246453, Example 66::US10662184, Example 66::US10815229, Example 66::US11299490, Example 66
SMILES Clc1cc(ccc1N[C@@H]1CCN(Cc2ccccc2)C1)S(=O)(=O)Nc1ncns1
InChI Key InChIKey=RGZJDZOTNRSBIE-OAHLLOKOSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 373799
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: 144nMAssay Description:Sodium currents were measured using the patch clamp technique in the whole-cell configuration using either a PatchXpress automated voltage clamp or m...More data for this Ligand-Target Pair