BDBM374263 (S)-(6-(6-(6-(1-aminobutyl)pyrazin-2-yl)-1H-indazol-1-yl)pyridin-2-yl)methanol::US10246456, Example 407::US10246456, Example 408

SMILES Brc1cncc(Br)n1

InChI Key InChIKey=JXKQTRCEKQCAGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 374263   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM374263((S)-(6-(6-(6-(1-aminobutyl)pyrazin-2-yl)-1H-indazo...)
Affinity DataIC50: <100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM374263((S)-(6-(6-(6-(1-aminobutyl)pyrazin-2-yl)-1H-indazo...)
Affinity DataIC50: <100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
In DepthDetails US Patent