BDBM374614 US10246457, Example 23
SMILES CC(C)(C)c1cc(F)c2c(cnn(-c3cccc(-c4cc(-c5cnn(CC(O)=O)c5)c5[nH]nc(N)c5c4)c3CO)c2=O)c1
InChI Key InChIKey=ZQRWMQKJXRMRAA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 374614
Affinity DataIC50: 20nMAssay Description:Btk enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (lime-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMAssay Description:Btk enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (lime-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair