BDBM374670 3-((S)-1-(1-(1-((R)-1-(2,4-Dichlorophenyl)ethyl)-3-methyl-1H-pyrazolo[3,4-b]pyrazin-6-yl)piperidin-4-yl)pyrrolidin-2-yl)propanoic acid 2,2,2-trifluoroacetate::US10246462, Example 51
SMILES C[C@H](c1ccc(Cl)cc1Cl)n1nc(C)c2ncc(nc12)N1CCC(CC1)N1CCC[C@H]1CCC(O)=O
InChI Key InChIKey=OBNKRARARXXTRX-MJGOQNOKSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 374670
Affinity DataIC50: 300nMAssay Description:To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...More data for this Ligand-Target Pair