BDBM374717 10-fluoro-7-methyl-7,8,15,16-tetrahydro-3,6- ethenoimidazo[5,1- f][1,4,7,8,10]benzoxatetraazacyclotridecin-17(14H)- one::US10246466, Example 42::US10618912, Example 42

SMILES CN1Cc2cc(F)ccc2OCCNC(=O)c2cnc3ccc1nn23

InChI Key InChIKey=XMQOCSTWSHBZGY-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 374717   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Turning Point Therapeutics

US Patent
LigandPNGBDBM374717(10-fluoro-7-methyl-7,8,15,16-tetrahydro-3,6- ethen...)
Affinity DataKd:  0.0880nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Turning Point Therapeutics

US Patent
LigandPNGBDBM374717(10-fluoro-7-methyl-7,8,15,16-tetrahydro-3,6- ethen...)
Affinity DataKd:  0.0880nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent