BDBM375479 US9907800, Example A188

SMILES CCN1CCN(CC1)c1ccc(\C=C\c2n[nH]c3cc(ccc23)C2C[C@@]22C(=O)Nc3ccc(OC)cc23)cc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 375479   

TargetAurora kinase B(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM375479(US9907800, Example A188)
Affinity DataIC50: <100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM375479(US9907800, Example A188)
Affinity DataIC50: <100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent