BDBM376115 N-(3-(2-amino-2-oxoethyl)-1- (4-fluorophenyl)-1H-pyrazol- 5-yl)-2-fluoro-5-(1-methyl- 1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 111

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2cc(CC(O)=O)nn2-c2ccc(F)cc2)c(F)cc1C(F)(F)F

InChI Key InChIKey=COYRAESDFMKJJS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376115   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376115(N-(3-(2-amino-2-oxoethyl)-1- (4-fluorophenyl)-1H-p...)
Affinity DataIC50:  2.40nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent