BDBM376994 N-[2-Methoxy-4-(piperidin-4-yl)phenyl]-7-(2-methoxyphenyl)-6-methylthieno[3,2-d]pyrimidin-2-amine ::US10259816, Compound 8::US10611770, Compound 8

SMILES COc1ccccc1-c1c(C)sc2cnc(Nc3ccc(cc3OC)C3CCNCC3)nc12

InChI Key InChIKey=SAHKGYKZRQOJEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 376994   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM376994(N-[2-Methoxy-4-(piperidin-4-yl)phenyl]-7-(2-methox...)
Affinity DataIC50:  6.40nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM376994(N-[2-Methoxy-4-(piperidin-4-yl)phenyl]-7-(2-methox...)
Affinity DataIC50:  6.40nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent