BDBM377006 8-(4-Fluoro-2-methoxyphenyl)-N-[3-(piperidin-4-yl)-1-isopropyl-1H-pyrazol-5-yl]quinazolin-2-amine ::US10259816, Compound 28::US10611770, Compound 28
SMILES COc1cc(F)ccc1-c1cccc2cnc(Nc3cc(nn3C(C)C)C3CCNCC3)nc12
InChI Key InChIKey=GZCMAQNHVNWLPT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 377006
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Guangzhou Maxinovel Pharmaceuticals
US Patent
Guangzhou Maxinovel Pharmaceuticals
US Patent
Affinity DataIC50: 34nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Guangzhou Maxinovel Pharmaceuticals
US Patent
Guangzhou Maxinovel Pharmaceuticals
US Patent
Affinity DataIC50: 34nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair