BDBM377018 N-[2,2-dimethyl-4-(piperidin-4-yl)-2,3-dihydro-1-benzofuran-7-yl]-7-(2-methoxyphenyl)-6-methylthieno[3,2-d]pyrimidin-2-amine ::US10259816, Compound 43::US10611770, Compound 43
SMILES COc1ccccc1C1=C(C)SC2C=NC(Nc3ccc(C4CCNCC4)c4CC(C)(C)Oc34)=NC12
InChI Key InChIKey=GDBNQUOZDVCWKF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 377018
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Guangzhou Maxinovel Pharmaceuticals
US Patent
Guangzhou Maxinovel Pharmaceuticals
US Patent
Affinity DataIC50: 10.9nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Guangzhou Maxinovel Pharmaceuticals
US Patent
Guangzhou Maxinovel Pharmaceuticals
US Patent
Affinity DataIC50: 10.9nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair