BDBM377920 N-((3-chloro-6-fluoro-1H-indol-5- yl)methyl)-2-((3-chloro-8-cyanoquinolin-6- yl)methyl)isonicotinamide::US10266515, Example 49

SMILES Fc1cc2[nH]cc(Cl)c2cc1CNC(=O)c1ccnc(Cc2cc(C#N)c3ccc(Cl)cc3c2)c1

InChI Key InChIKey=LAGIQPIPYAXKJV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 377920   

TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM377920(N-((3-chloro-6-fluoro-1H-indol-5- yl)methyl)-2-((3...)
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent