BDBM378878 US10266535, Compound 77
SMILES CC(C)C[C@H](N)C(=O)NC1CCC(CC1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12
InChI Key InChIKey=WRXSDAGHMRWWGB-VUNKPPBISA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 378878
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hefei Institutes of Physical Science, Chinese Academy of Sciences
US Patent
Hefei Institutes of Physical Science, Chinese Academy of Sciences
US Patent
Affinity DataIC50: 18nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hefei Institutes of Physical Science, Chinese Academy of Sciences
US Patent
Hefei Institutes of Physical Science, Chinese Academy of Sciences
US Patent
Affinity DataIC50: 128nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair
TargetDimer of Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hefei Institutes of Physical Science, Chinese Academy of Sciences
US Patent
Hefei Institutes of Physical Science, Chinese Academy of Sciences
US Patent
Affinity DataIC50: 24nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair