BDBM378882 US10266535, Compound 45

SMILES CC(C)[C@@H](N)C(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12

InChI Key InChIKey=DASBULWGLYMECT-AUSIDOKSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 378882   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hefei Institutes of Physical Science, Chinese Academy of Sciences

US Patent
LigandPNGBDBM378882(US10266535, Compound 45)
Affinity DataIC50:  260nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hefei Institutes of Physical Science, Chinese Academy of Sciences

US Patent
LigandPNGBDBM378882(US10266535, Compound 45)
Affinity DataIC50:  32nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent