BDBM378919 US10266548, Example 2-11-1::methyl 3-chloro- 4-({3-[5- methoxy-4- (pyridin-4- ylamino) pyrimidin- 2-yl]-1H-indazol- 1- yl}methyl) benzoate

SMILES COC(=O)c1ccc(Cn2nc(-c3ncc(OC)c(Nc4ccncc4)n3)c3ccccc23)c(Cl)c1

InChI Key InChIKey=YGEJZWNWYDVTHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378919   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM378919(US10266548, Example 2-11-1 | methyl 3-chloro- 4-({...)
Affinity DataIC50:  7.10nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent