BDBM378919 US10266548, Example 2-11-1::methyl 3-chloro- 4-({3-[5- methoxy-4- (pyridin-4- ylamino) pyrimidin- 2-yl]-1H-indazol- 1- yl}methyl) benzoate
SMILES COC(=O)c1ccc(Cn2nc(-c3ncc(OC)c(Nc4ccncc4)n3)c3ccccc23)c(Cl)c1
InChI Key InChIKey=YGEJZWNWYDVTHN-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 378919
TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 7.10nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair