BDBM378999 2-[1-(2- fluorobenzyl)- 1H-indazol-3-yl]- 5-{[3- (methoxymethyl)- 1,2,4- oxadiazol-5- yl]methoxy}-N- (pyridin-4- yl)pyrimidin-4- amine::US10266548, Example 4-13

SMILES COCc1noc(COc2cnc(nc2Nc2ccncc2)-c2nn(Cc3ccccc3F)c3ccccc23)n1

InChI Key InChIKey=XSFFAXPPGGARNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 378999   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM378999(2-[1-(2- fluorobenzyl)- 1H-indazol-3-yl]- 5-{[3- (...)
Affinity DataIC50:  76nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM378999(2-[1-(2- fluorobenzyl)- 1H-indazol-3-yl]- 5-{[3- (...)
Affinity DataIC50:  7.60nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent