BDBM379043 2-({2-[1-(2- fluorobenzyl)- 1H-indazol-3-yl]- 4-(pyridin-4- ylamino) pyrimidin- 5-yl}oxy)ethanol::US10266548, Example 13-2
SMILES OCCOc1cnc(nc1Nc1ccncc1)-c1nn(Cc2ccccc2F)c2ccccc12
InChI Key InChIKey=SFPNOAKQBIIDHK-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 379043
TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 7.20nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair