BDBM379064 ({2-[1-(4-ethoxy- 2,6- difluorobenzyl)- 1H-indazol-3-yl]- 4-(pyridin-4- yla- mino)pyrimidin-5- yl}oxy)acetic acid::US10266548, Example 19-2

SMILES CCOc1cc(F)c(Cn2nc(-c3ncc(OCC(O)=O)c(Nc4ccncc4)n3)c3ccccc23)c(F)c1

InChI Key InChIKey=PKXPPDSDTAVNGD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 379064   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM379064(({2-[1-(4-ethoxy- 2,6- difluorobenzyl)- 1H-indazol...)
Affinity DataIC50:  6.30nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent