BDBM379083 4-({5-methoxy-2-[1- (4-propylbenzyl)- 1H-indazol-3- yl]pyrimidin-4- yl}amino)pyridine-3- carboxamide::US10266548, Example 25-2

SMILES CCCc1ccc(Cn2nc(-c3ncc(OC)c(Nc4ccncc4C(N)=O)n3)c3ccccc23)cc1

InChI Key InChIKey=NXOUTCZKYGEGHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 379083   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM379083(4-({5-methoxy-2-[1- (4-propylbenzyl)- 1H-indazol-3...)
Affinity DataIC50:  5.40nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent