BDBM379083 4-({5-methoxy-2-[1- (4-propylbenzyl)- 1H-indazol-3- yl]pyrimidin-4- yl}amino)pyridine-3- carboxamide::US10266548, Example 25-2
SMILES CCCc1ccc(Cn2nc(-c3ncc(OC)c(Nc4ccncc4C(N)=O)n3)c3ccccc23)cc1
InChI Key InChIKey=NXOUTCZKYGEGHY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 379083
TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 5.40nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair