BDBM381926 5-(4-(4-chloro-2-fluorophenoxy)piperidin-1-yl)-6-(isopropylamino)pyrazine-2,3-dicarbonitrile::US10000468, Example 5::US10273225, Example 5

SMILES CC(C)Nc1nc(C#N)c(nc1N1CCC(CC1)Oc1ccc(Cl)cc1F)C#N

InChI Key InChIKey=CHDNZVHJOJQCDP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 381926   

TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM381926(5-(4-(4-chloro-2-fluorophenoxy)piperidin-1-yl)-6-(...)
Affinity DataEC50:  3.27E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM381926(5-(4-(4-chloro-2-fluorophenoxy)piperidin-1-yl)-6-(...)
Affinity DataEC50:  3.27E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent