BDBM381930 US10273211, Compound 7

SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(O)=O)cc3)c2cc1OC

InChI Key InChIKey=HXGYPQKHBCZWKO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 381930   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM381930(US10273211, Compound 7)
Affinity DataIC50: >1.00E+4nMAssay Description:Kinase Activity was measured and profiled by EMD Millipore according to the Kinase Profiler Service Assay Protocols Protocol Guide Volume 57. The res...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM381930(US10273211, Compound 7)
Affinity DataIC50:  2.75E+3nMAssay Description:Kinase Activity was measured and profiled by EMD Millipore according to the Kinase Profiler Service Assay Protocols Protocol Guide Volume 57. The res...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM381930(US10273211, Compound 7)
Affinity DataIC50:  2.75E+3nMAssay Description:Kinase Activity was measured and profiled by EMD Millipore according to the Kinase Profiler Service Assay Protocols Protocol Guide Volume 57. The res...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM381930(US10273211, Compound 7)
Affinity DataIC50: >1.00E+4nMAssay Description:Kinase Activity was measured and profiled by EMD Millipore according to the Kinase Profiler Service Assay Protocols Protocol Guide Volume 57. The res...More data for this Ligand-Target Pair
In DepthDetails US Patent