BDBM382114 6-(4-(2,4-difluorophenoxy)piperidin-1-yl)-N-(2-(dimethylamino)-ethyl)-5-(isopropylamino)-N-methylpyrazine-2-carboxamide::US10000468, Example 23::US10273225, Example 23

SMILES CC(C)Nc1ncc(nc1N1CCC(CC1)Oc1ccc(F)cc1F)C(=O)N(C)CCN(C)C

InChI Key InChIKey=QXJXTGIUKCRPNA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 382114   

TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM382114(6-(4-(2,4-difluorophenoxy)piperidin-1-yl)-N-(2-(di...)
Affinity DataEC50:  1.72E+5nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM382114(6-(4-(2,4-difluorophenoxy)piperidin-1-yl)-N-(2-(di...)
Affinity DataEC50:  1.72E+5nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent