BDBM382122 US10000468, Example 31::US10273225, Example 31

SMILES CC(C)Nc1nc(cnc1N1CCC(CC1)[C@@H](F)c1ccc(F)cc1F)C#N

InChI Key InChIKey=QENDOAGTFPJVJN-GOSISDBHSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 382122   

TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM382122(US10000468, Example 31 | US10273225, Example 31)
Affinity DataEC50:  1.80E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM382122(US10000468, Example 31 | US10273225, Example 31)
Affinity DataEC50:  1.80E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent